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Target
Uracil-DNA glycosylase
Ligand
BDBM50343401
Substrate
n/a
Meas. Tech.
ChEMBL_747132 (CHEMBL1777498)
IC50
221000±n/a nM
Citation
 Nuth, M; Huang, L; Saw, YL; Schormann, N; Chattopadhyay, D; Ricciardi, RP Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4. J Med Chem 54:3260-7 (2011) [PubMed]  Article 
Target
Name:
Uracil-DNA glycosylase
Synonyms:
OPG116 | UDG | UNG | UNG_VACCW
Type:
PROTEIN
Mol. Mass.:
25071.48
Organism:
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strainWR))
Description:
ChEMBL_747132
Residue:
218
Sequence:
MNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDKFFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISRLTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHITKHVSVLYCLGKTDYSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEIINVLLELDNKAPINWAQGFIY
  
Inhibitor
Name:
BDBM50343401
Synonyms:
(4R)-4-(2-chlorophenyl)-8-ethoxy-3a,4,5,9b-tetrahydro-1H-cyclopenta[c]quinoline | CHEMBL1774937
Type:
Small organic molecule
Emp. Form.:
C20H20ClNO
Mol. Mass.:
325.832
SMILES:
CCOc1ccc2N[C@H](C3C=CCC3c2c1)c1ccccc1Cl |r,c:10|
Structure:
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