Reaction Details Report a problem with these data
Target
Matrix protein 2 [1-96]
Ligand
BDBM50343541
Substrate
n/a
Meas. Tech.
ChEMBL_747076 (CHEMBL1777442)
IC50
7100±n/a nM
Citation
 Duque, MD; Ma, C; Torres, E; Wang, J; Naesens, L; Juárez-Jiménez, J; Camps, P; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. J Med Chem 54:2646-57 (2011) [PubMed]  Article 
Target
Name:
Matrix protein 2 [1-96]
Synonyms:
M | M2_I72A2 | Matrix protein 2
Type:
PROTEIN
Mol. Mass.:
11051.96
Organism:
Influenza A virus
Description:
ChEMBL_1453980
Residue:
96
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
  
Inhibitor
Name:
BDBM50343541
Synonyms:
C-(Hexahydro-2,5-methano-pentalen-3a-yl)-methylamine | CHEMBL506460 | [(Tricyclo[3.3.1.03,7]non-3-yl)methyl]amine
Type:
Small organic molecule
Emp. Form.:
C10H17N
Mol. Mass.:
151.2487
SMILES:
NCC12CC3CC1CC(C2)C3 |TLB:3:2:10.4.5:7,THB:3:4:7:9.2,1:2:10.4.5:7|
Structure:
Search PDB for entries with ligand similarity: