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Target
Matrix protein 2 [1-96]
Ligand
BDBM50343543
Substrate
n/a
Meas. Tech.
ChEMBL_747076 (CHEMBL1777442)
IC50
2400±n/a nM
Citation
 Duque, MD; Ma, C; Torres, E; Wang, J; Naesens, L; Juárez-Jiménez, J; Camps, P; Luque, FJ; DeGrado, WF; Lamb, RA; Pinto, LH; Vázquez, S Exploring the size limit of templates for inhibitors of the M2 ion channel of influenza A virus. J Med Chem 54:2646-57 (2011) [PubMed]  Article 
Target
Name:
Matrix protein 2 [1-96]
Synonyms:
M | M2_I72A2 | Matrix protein 2
Type:
PROTEIN
Mol. Mass.:
11051.96
Organism:
Influenza A virus
Description:
ChEMBL_1453980
Residue:
96
Sequence:
MSLLTEVETPIRNEWGCRCNDSSDPLVVAASIIGILHLILWILDRLFFKCIYRFFEHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVSIEL
  
Inhibitor
Name:
BDBM50343543
Synonyms:
CHEMBL499125 | N-(Hexahydro-2,5-methano-pentalen-3a-ylmethyl)-guanidine | N-[(Tricyclo[3.3.1.03,7]non-3-yl)methyl]guanidine
Type:
Small organic molecule
Emp. Form.:
C11H19N3
Mol. Mass.:
193.2887
SMILES:
[#7]\[#6](-[#7])=[#7]/[#6]C12[#6]-[#6]-3-[#6]-[#6]1-[#6]-[#6](-[#6]2)-[#6]-3 |TLB:10:9:13.11.12:6,THB:10:11:8.9:6|
Structure:
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