Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50347163
Substrate
n/a
Meas. Tech.
ChEMBL_753521 (CHEMBL1798229)
Ki
1.05±n/a nM
Citation
 Nagase, H; Watanabe, A; Nemoto, T; Nakajima, M; Hasebe, K; Mochizuki, H; Fujii, H Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. 1: Synthesis of triplet drugs with morphinan skeletons. Bioorg Med Chem Lett 21:4023-6 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50347163
Synonyms:
CHEMBL1797517
Type:
Small organic molecule
Emp. Form.:
C54H60N4O12
Mol. Mass.:
957.0738
SMILES:
CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CC[C@]41O[C@@H]2N3[C@H]1O[C@]1(CC[C@@]4(O)[C@H]6Cc7ccc(O)c8O[C@@H]1[C@]4(CCN6C)c78)[C@@H]3O[C@]21CC[C@@]2(O)[C@H]3Cc4ccc(O)c6O[C@@H]1[C@]2(CCN3C)c46)ccc5O |r|
Structure:
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