Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM50347635
Substrate
n/a
Meas. Tech.
ChEMBL_755707 (CHEMBL1803209)
Ki
270±n/a nM
Citation
 Kühhorn, J; Hübner, H; Gmeiner, P Bivalent dopamine D2 receptor ligands: synthesis and binding properties. J Med Chem 54:4896-903 (2011) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50347635
Synonyms:
CHEMBL1803029
Type:
Small organic molecule
Emp. Form.:
C56H76N10O9
Mol. Mass.:
1033.2642
SMILES:
COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCCc1cn(CCOCCOCCOCCn2cc(CCCOc3ccc(CN4CCN(CC4)c4ccccc4OC)cc3OC)nn2)nn1
Structure:
Search PDB for entries with ligand similarity: