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Target
D(2) dopamine receptor
Ligand
BDBM50347634
Substrate
n/a
Meas. Tech.
ChEMBL_755708 (CHEMBL1803210)
Ki
2.8±n/a nM
Citation
 Kühhorn, J; Hübner, H; Gmeiner, P Bivalent dopamine D2 receptor ligands: synthesis and binding properties. J Med Chem 54:4896-903 (2011) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50347634
Synonyms:
CHEMBL1803028
Type:
Small organic molecule
Emp. Form.:
C54H72N10O8
Mol. Mass.:
989.2117
SMILES:
COc1cc(CN2CCN(CC2)c2ccccc2OC)ccc1OCCCc1cn(CCOCCOCCn2cc(CCCOc3ccc(CN4CCN(CC4)c4ccccc4OC)cc3OC)nn2)nn1
Structure:
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