Reaction Details Report a problem with these data
Target
Testis-specific serine/threonine-protein kinase 2
Ligand
BDBM50348621
Substrate
n/a
Meas. Tech.
ChEMBL_755626 (CHEMBL1805366)
IC50
>10000±n/a nM
Citation
 Belanger, DB; Curran, PJ; Hruza, A; Voigt, J; Meng, Z; Mandal, AK; Siddiqui, MA; Basso, AD; Gray, K Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors. Bioorg Med Chem Lett 20:5170-4 (2010) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 2
Synonyms:
DGSG | SPOGA2 | STK22B | TSSK2 | TSSK2_HUMAN
Type:
PROTEIN
Mol. Mass.:
40954.93
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1459845
Residue:
358
Sequence:
MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
  
Inhibitor
Name:
BDBM50348621
Synonyms:
CHEMBL1270795
Type:
Small organic molecule
Emp. Form.:
C14H13N7S2
Mol. Mass.:
343.43
SMILES:
CSc1cn2c(cnc2c(Nc2cc(C)ns2)n1)-c1cn[nH]c1
Structure:
Search PDB for entries with ligand similarity: