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Target
Ricin
Ligand
BDBM6645
Substrate
n/a
Meas. Tech.
ChEMBL_764841 (CHEMBL1826784)
IC50
600000±n/a nM
Citation
 Pruet, JM; Jasheway, KR; Manzano, LA; Bai, Y; Anslyn, EV; Robertus, JD 7-Substituted pterins provide a new direction for ricin A chain inhibitors. Eur J Med Chem 46:3608-15 (2011) [PubMed]  Article 
Target
Name:
Ricin
Synonyms:
RICI_RICCO
Type:
PROTEIN
Mol. Mass.:
64090.82
Organism:
Ricinus communis
Description:
ChEMBL_1286970
Residue:
576
Sequence:
MKPGGNTIVIWMYAVATWLCFGSTSGWSFTLEDNNIFPKQYPIINFTTAGATVQSYTNFIRAVRGRLTTGADVRHEIPVLPNRVGLPINQRFILVELSNHAELSVTLALDVTNAYVVGYRAGNSAYFFHPDNQEDAEAITHLFTDVQNRYTFAFGGNYDRLEQLAGNLRENIELGNGPLEEAISALYYYSTGGTQLPTLARSFIICIQMISEAARFQYIEGEMRTRIRYNRRSAPDPSVITLENSWGRLSTAIQESNQGAFASPIQLQRRNGSKFSVYDVSILIPIIALMVYRCAPPPSSQFSLLIRPVVPNFNADVCMDPEPIVRIVGRNGLCVDVRDGRFHNGNAIQLWPCKSNTDANQLWTLKRDNTIRSNGKCLTTYGYSPGVYVMIYDCNTAATDATRWQIWDNGTIINPRSSLVLAATSGNSGTTLTVQTNIYAVSQGWLPTNNTQPFVTTIVGLYGLCLQANSGQVWIEDCSSEKAEQQWALYADGSIRPQQNRDNCLTSDSNIRETVVKILSCGPASSGQRWMFKNDGTILNLYSGLVLDVRASDPSLKQIILYPLHGDPNQIWLPLF
  
Inhibitor
Name:
BDBM6645
Synonyms:
4-{[(2-amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid | CHEMBL341824 | Pteridine deriv. 12
Type:
Small organic molecule
Emp. Form.:
C14H12N6O3
Mol. Mass.:
312.2835
SMILES:
Nc1nc2ncc(CNc3ccc(cc3)C(O)=O)nc2c(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: