Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50354845
Substrate
n/a
Meas. Tech.
ChEMBL_772346 (CHEMBL1838791)
Ki
1709±n/a nM
Citation
 Teng, H; Thakur, GA; Makriyannis, A Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorg Med Chem Lett 21:5999-6002 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50354845
Synonyms:
CHEMBL1834523
Type:
Small organic molecule
Emp. Form.:
C18H11F6NO4S
Mol. Mass.:
451.34
SMILES:
FC(F)(F)CCCS(=O)(=O)Oc1ccc2oc3c(C#N)c(ccc3c2c1)C(F)(F)F
Structure:
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