Reaction Details Report a problem with these data
Target
UDP-glucuronosyltransferase 1A10
Ligand
BDBM13066
Substrate
n/a
Meas. Tech.
ChEMBL_774121 (CHEMBL1908126)
Ki
28000±n/a nM
Citation
 Kiang, TK; Ensom, MH; Chang, TK UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther 106:97-132 (2005) [PubMed]  Article 
Target
Name:
UDP-glucuronosyltransferase 1A10
Synonyms:
GNT1 | UD110_HUMAN | UDP-glucuronosyltransferase 1-10 | UDP-glucuronosyltransferase 1-J | UDP-glucuronosyltransferase 1A10 | UDPGT 1-10 | UGT-1J | UGT1 | UGT1*10 | UGT1-10 | UGT1.10 | UGT1A10 | UGT1J
Type:
PROTEIN
Mol. Mass.:
59817.97
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1491709
Residue:
530
Sequence:
MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
  
Inhibitor
Name:
BDBM13066
Synonyms:
2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid | CHEMBL139 | Diclofenac | US11337935, Compound Diclofenac | US11478464, Compound Diclofenac | US11786535, Compound Diclofenac | {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid
Type:
Small organic molecule
Emp. Form.:
C14H11Cl2NO2
Mol. Mass.:
296.149
SMILES:
OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
Structure:
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