Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50355851
Substrate
n/a
Meas. Tech.
ChEMBL_775144 (CHEMBL1912449)
Ki
5000±n/a nM
Citation
 Packiarajan, M; Coate, H; Desai, M; Jimenez, HN; Reinhard, EJ; Jubian, VJ; Marzabadi, MR; Chandrasena, G; Wolinski, TC; Walker, MW; Andersen, K 5-(2'-Pyridyl)-2-aminothiazoles: alkyl amino sulfonamides and sulfamides as potent NPY(5) antagonists. Bioorg Med Chem Lett 21:6500-4 (2011) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50355851
Synonyms:
CHEMBL1909724
Type:
Small organic molecule
Emp. Form.:
C17H25N5O2S2
Mol. Mass.:
395.543
SMILES:
CC(C)S(=O)(=O)N1CCN(CCNc2nc(cs2)-c2ccccn2)CC1
Structure:
Search PDB for entries with ligand similarity: