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Target
Kappa-type opioid receptor
Ligand
BDBM50357429
Substrate
n/a
Meas. Tech.
ChEMBL_788481 (CHEMBL1918284)
Ki
197±n/a nM
Citation
 Rossi, D; Pedrali, A; Urbano, M; Gaggeri, R; Serra, M; Fernández, L; Fernández, M; Caballero, J; Ronsisvalle, S; Prezzavento, O; Schepmann, D; Wuensch, B; Peviani, M; Curti, D; Azzolina, O; Collina, S Identification of a potent and selectives¿? receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells. Bioorg Med Chem 19:6210-24 (2011) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50357429
Synonyms:
CHEMBL1917702
Type:
Small organic molecule
Emp. Form.:
C19H23NO
Mol. Mass.:
281.392
SMILES:
COc1ccc(cc1)C(\C)=C\CN(C)Cc1ccccc1
Structure:
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