Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50359750
Substrate
n/a
Meas. Tech.
ChEMBL_791613 (CHEMBL1930837)
Ki
6.4±n/a nM
Citation
 Huber, D; Löber, S; Hübner, H; Gmeiner, P Bivalent molecular probes for dopamine D2-like receptors. Bioorg Med Chem 20:455-66 (2011) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50359750
Synonyms:
CHEMBL1928133
Type:
Small organic molecule
Emp. Form.:
C26H35N5O4
Mol. Mass.:
481.5872
SMILES:
CCOCCOc1ccn2ncc(C(=O)NCCCN3CCN(CC3)c3ccccc3OC)c2c1
Structure:
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