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Target
Beta-2 adrenergic receptor
Ligand
BDBM50361247
Substrate
n/a
Meas. Tech.
ChEMBL_795270 (CHEMBL1937030)
Ki
5623±n/a nM
Citation
 Soriano-Ursúa, MA; McNaught-Flores, DA; Nieto-Alamilla, G; Segura-Cabrera, A; Correa-Basurto, J; Arias-Montaño, JA; Trujillo-Ferrara, JG Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the humanß2-adrenoceptor. Bioorg Med Chem 20:933-41 (2012) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50361247
Synonyms:
ALBUTEROL | LEVOSALBUTAMOL | Levalbuterol | Levolin
Type:
Small organic molecule
Emp. Form.:
C13H21NO3
Mol. Mass.:
239.3107
SMILES:
CC(C)(C)NC[C@H](O)c1ccc(O)c(CO)c1 |r|
Structure:
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