Reaction Details Report a problem with these data
Target
Met repressor
Ligand
BDBM50362016
Substrate
n/a
Meas. Tech.
ChEMBL_799628 (CHEMBL1941334)
EC50
150±n/a nM
Citation
 Joce, C; White, R; Stockley, PG; Warriner, S; Turnbull, WB; Nelson, A Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues. Bioorg Med Chem Lett 22:278-84 (2011) [PubMed]  Article 
Target
Name:
Met repressor
Synonyms:
Met regulon regulatory protein MetJ
Type:
PROTEIN
Mol. Mass.:
12138.09
Organism:
Escherichia coli
Description:
ChEMBL_799627
Residue:
105
Sequence:
MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
  
Inhibitor
Name:
BDBM50362016
Synonyms:
CHEMBL1939724
Type:
Small organic molecule
Emp. Form.:
C19H32N7O4
Mol. Mass.:
422.5013
SMILES:
CCCNC(=O)CCC[N+](C)(C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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