Reaction Details
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Riboflavin-binding protein
Ligand
BDBM50362896
Substrate
n/a
Meas. Tech.
ChEMBL_800333 (CHEMBL1948179)
Kd
35500±n/a nM
Citation
Plantinga, A; Witte, A; Li, MH; Harmon, A; Choi, SK; Banaszak Holl, MM; Orr, BG; Baker, JR; Sinniah, K Bioanalytical Screening of Riboflavin Antagonists for Targeted Drug Delivery - A Thermodynamic and Kinetic Study. ACS Med Chem Lett 2:363-367 (2011) [PubMed] Article More Info.:
Target
Name:
Riboflavin-binding protein
Synonyms:
RBP | RBP_CHICK | Riboflavin-binding protein, plasma form | Riboflavin-binding protein, yolk major form | Riboflavin-binding protein, yolk minor form
Type:
PROTEIN
Mol. Mass.:
27203.20
Organism:
Gallus gallus
Description:
ChEMBL_800332
Residue:
238
Sequence:
MLRFAITLFAVITSSTCQQYGCLEGDTHKANPSPEPNMHECTLYSESSCCYANFTEQLAHSPIIKVSNSYWNRCGQLSKSCEDFTKKIECFYRCSPHAARWIDPRYTAAIQSVPLCQSFCDDWYEACKDDSICAHNWLTDWERDESGENHCKSKCVPYSEMYANGTDMCQSMWGESFKVSESSCLCLQMNKKDMVAIKHLLSESSEESSSMSSSEEHACQKKLLKFEALQQEEGEERR
Inhibitor
Name:
BDBM50362896
Synonyms:
CHEMBL1946750
Type:
Small organic molecule
Emp. Form.:
C22H30N6O7
Mol. Mass.:
490.5096
SMILES:
Cc1cc2nc3c(nc(=O)n(CC(=O)NCCCN)c3=O)n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C |r|
Structure:
