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Target
D(1B) dopamine receptor
Ligand
BDBM50363963
Substrate
n/a
Meas. Tech.
ChEMBL_803949 (CHEMBL1954780)
Ki
4.4±n/a nM
Citation
 Robaa, D; Enzensperger, C; Eldin Abulazm, S; Hefnawy, MM; El-Subbagh, HI; Wani, TA; Lehmann, J Chiral indolo[3,2-f][3]benzazecine-type dopamine receptor antagonists: synthesis and activity of racemic and enantiopure derivatives. J Med Chem 54:7422-6 (2011) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
DOPAMINE D5 | dopamine receptor D5 | D(5) dopamine receptor | D1beta dopamine receptor | DRD5_HUMAN | DRD5 | DRD1B | DRD1L2
Type:
Protein
Mol. Mass.:
52943.41
Organism:
Human
Description:
P21918
Residue:
477
Sequence:
MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYAFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
  
Inhibitor
Name:
BDBM50363963
Synonyms:
CHEMBL1949725
Type:
Small organic molecule
Emp. Form.:
C21H24N2
Mol. Mass.:
n/a
SMILES:
C[C@H]1Cc2c(Cc3ccccc3CCN1C)[nH]c1ccccc21 |r|
Structure:
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