Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50364531
Substrate
n/a
Meas. Tech.
ChEMBL_802809 (CHEMBL1953543)
IC50
>10000±n/a nM
Citation
 Liu, JJ; Wang, Y; Johnson, MG; Li, AR; Shen, W; Wang, X; Su, Y; Brown, M; Van Lengerich, B; Rickel, E; Martin, T; Budelsky, A; Seitz, L; Danao, J; Tang, HL; Collins, T; Medina, JC Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists. Bioorg Med Chem Lett 22:1686-9 (2012) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50364531
Synonyms:
CHEMBL1950874
Type:
Small organic molecule
Emp. Form.:
C25H24Cl2N2O7S2
Mol. Mass.:
599.503
SMILES:
CCCCNC(=O)c1ccc(c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1)S(=O)(=O)c1ccc(CC(O)=O)cc1
Structure:
Search PDB for entries with ligand similarity: