Reaction Details Report a problem with these data
Target
4-aminobutyrate aminotransferase, mitochondrial
Ligand
BDBM17663
Substrate
n/a
Meas. Tech.
ChEBML_70657
Ki
2400000±n/a nM
Citation
 Hopkins, MH; Silverman, RB -Amino acid analogues as mechanism-based inactivators of -aminobutyric acid aminotransferase Bioorg Med Chem Lett 2:1371-1374 (1992)    Article 
Target
Name:
4-aminobutyrate aminotransferase, mitochondrial
Synonyms:
(S)-3-amino-2-methylpropionate transaminase | 2.6.1.19 | 2.6.1.22 | 4-aminobutyrate aminotransferase, mitochondrial | ABAT | GABA aminotransferase | GABA transaminase | GABA-AT | GABA-T | GABAT | GABT_PIG | Gamma-amino-N-butyrate transaminase | L-AIBAT
Type:
n/a
Mol. Mass.:
56633.06
Organism:
Sus scrofa
Description:
n/a
Residue:
500
Sequence:
MASVLLTRRLACSFRHNHRLLVPGWRHISQAAAKVDVEFDYDGPLMKTEVPGPRSRELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSIPIGYSHPALVKLVQQPQNVSTFINRPALGILPPENFVEKLRESLLSVAPKGMSQLITMACGSCSNENAFKTIFMWYRSKERGQSAFSKEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDISRKHGCAFLVDEVQTGGGSTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLSNAAHAGKVLLTGLLDLQARYPQFISRVRGRGTFCSFDTPDESIRNKLISIARNKGVMLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK
  
Inhibitor
Name:
BDBM17663
Synonyms:
(2S)-2-amino-3-(sulfooxy)propanoic acid | L-SOS | L-serine O-sulfate | Sulfoserine
Type:
Small organic molecule
Emp. Form.:
C3H7NO6S
Mol. Mass.:
185.156
SMILES:
N[C@@H](COS(O)(=O)=O)C(O)=O
Structure:
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