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Target
Adenosylhomocysteinase
Ligand
BDBM50281614
Substrate
n/a
Meas. Tech.
ChEBML_197376
IC50
>100000±n/a nM
Citation
 Siddiqi, SM; Raissian, M; Schneller, SW; Ikeda, S; Snoeck, R; Andrei, G; Balzarini, J; De Clerq, E ()-7-deazaaristeromycin lacking the hydroxymethyl substituent Bioorg Med Chem Lett 3:663-666 (1993)    Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50281614
Synonyms:
3-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-cyclopentane-1,2-diol | CHEMBL160308
Type:
Small organic molecule
Emp. Form.:
C11H14N4O2
Mol. Mass.:
234.2545
SMILES:
Nc1ncnc2n(ccc12)C1CCC(O)C1O
Structure:
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