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Target
D(2) dopamine receptor
Ligand
BDBM50123809
Substrate
n/a
Meas. Tech.
ChEBML_62253
Ki
>1000±n/a nM
Citation
 Langlois, M; Yang, D; Bremont, B; Shen, S Synthesis and pharmacological activity of a macrocyclic benzamide Bioorg Med Chem Lett 5:795-798 (1995)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50123809
Synonyms:
4-Amino-5-chloro-2-methoxy-N-(1-methyl-piperidin-4-yl)-benzamide | CHEMBL164425
Type:
Small organic molecule
Emp. Form.:
C14H20ClN3O2
Mol. Mass.:
297.781
SMILES:
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(C)CC1
Structure:
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