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Target
Neurotensin receptor type 1
Ligand
BDBM50366427
Substrate
n/a
Meas. Tech.
ChEBML_144282
Ki
0.150000±n/a nM
Citation
 Wustrow, D; Davis, M; Akunne, H; Corbin, A; Wiley, J; Wise, L; Heffner, T Reduced amide bond neurotensin 813 mimetics with potent in vivo activity Bioorg Med Chem Lett 5:997-1002 (1995)    Article 
Target
Name:
Neurotensin receptor type 1
Synonyms:
NT-R-1 | NTR1_MOUSE | Neurotensin 1 | Neurotensin receptor 1 | Neurotensin receptor type 1 | Ntsr | Ntsr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47237.04
Organism:
MOUSE
Description:
Neurotensin 1 NTSR1 MOUSE::A2ACT4
Residue:
424
Sequence:
MHLNSSVQQGAPSEPGAQPFPHPQFGLETMLLALSLSNGSGNSSESILEPNSNLDVNTDIYSKVLVTAVYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGLQNRSADGQHPGGLVCTPTVDTATVKVVIQVNTFMSFLFPMLIISILNTVIANKLTVMVHQAAEQGRGVCTVGTHNSLEHSTFNMSIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRRRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
  
Inhibitor
Name:
BDBM50366427
Synonyms:
CHEMBL1793865
Type:
Small organic molecule
Emp. Form.:
C38H66N8O7
Mol. Mass.:
746.98
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O
Structure:
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