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Target
Cholecystokinin receptor type A
Ligand
BDBM50288463
Substrate
n/a
Meas. Tech.
ChEBML_50193
IC50
>10000±n/a nM
Citation
 Semple, G; Ryder, H; Kendrick, DA; Batt, AR; Mathews, E; Rooker, DP; Szelke, M; Nishida, A; Miyata, K Identification and biological activity of novel peptidomimetic gastrin/CCK-B receptor agonists Bioorg Med Chem Lett 6:2971-2976 (1996)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50288463
Synonyms:
(R)-2-{(2R,5S)-2-[(R)-3-(Carboxymethyl-carbamoyl)-3,4-dihydro-1H-isoquinoline-2-carbonyl]-5-phenyl-pyrrolidine-1-carbonyl}-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester | CHEMBL318475
Type:
Small organic molecule
Emp. Form.:
C37H40N4O7
Mol. Mass.:
652.7361
SMILES:
CC(C)(C)OC(=O)N1[C@H](Cc2ccccc12)C(=O)N1[C@H](CC[C@H]1c1ccccc1)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(O)=O
Structure:
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