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Target
Cholesteryl ester transfer protein
Ligand
BDBM50366476
Substrate
n/a
Meas. Tech.
ChEBML_48926
IC50
19700±n/a nM
Citation
 Jeong, T; Ahn, J; Kim, Y; Bok, S; Kwon, B; Shin, J; Seo, Y CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria Undulata Bioorg Med Chem Lett 7:1481-1482 (1997)    Article 
Target
Name:
Cholesteryl ester transfer protein
Synonyms:
CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I
Type:
Enzyme
Mol. Mass.:
54751.53
Organism:
Homo sapiens (Human)
Description:
P11597
Residue:
493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
  
Inhibitor
Name:
BDBM50366476
Synonyms:
CHEMBL1159544
Type:
Small organic molecule
Emp. Form.:
C24H47NO7
Mol. Mass.:
461.6325
SMILES:
CCCCCCCCCCCCC\C=C\C(O)C(N)CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O |r|
Structure:
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