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Target
Cholesteryl ester transfer protein
Ligand
BDBM50240721
Substrate
n/a
Meas. Tech.
ChEBML_48926
IC50
6300±n/a nM
Citation
 Jeong, T; Ahn, J; Kim, Y; Bok, S; Kwon, B; Shin, J; Seo, Y CETP inhibitory activity of ceramides, isolated from the gorgonian Acabaria Undulata Bioorg Med Chem Lett 7:1481-1482 (1997)    Article 
Target
Name:
Cholesteryl ester transfer protein
Synonyms:
CETP | CETP_HUMAN | Cholesteryl ester transfer protein (CETP) | Lipid transfer protein I
Type:
Enzyme
Mol. Mass.:
54751.53
Organism:
Homo sapiens (Human)
Description:
P11597
Residue:
493
Sequence:
MLAATVLTLALLGNAHACSKGTSHEAGIVCRITKPALLVLNHETAKVIQTAFQRASYPDITGEKAMMLLGQVKYGLHNIQISHLSIASSQVELVEAKSIDVSIQNVSVVFKGTLKYGYTTAWWLGIDQSIDFEIDSAIDLQINTQLTCDSGRVRTDAPDCYLSFHKLLLHLQGEREPGWIKQLFTNFISFTLKLVLKGQICKEINVISNIMADFVQTRAASILSDGDIGVDISLTGDPVITASYLESHHKGHFIYKNVSEDLPLPTFSPTLLGDSRMLYFWFSERVFHSLAKVAFQDGRLMLSLMGDEFKAVLETWGFNTNQEIFQEVVGGFPSQAQVTVHCLKMPKISCQNKGVVVNSSVMVKFLFPRPDQQHSVAYTFEEDIVTTVQASYSKKKLFLSLLDFQITPKTVSNLTESSSESVQSFLQSMITAVGIPEVMSRLEVVFTALMNSKGVSLFDIINPEIITRDGFLLLQMDFGFPEHLLVDFLQSLS
  
Inhibitor
Name:
BDBM50240721
Synonyms:
(E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol | CHEMBL322333 | N,N-Dimethylsphingosine | N,N-dimethylspingosine | dimethylspingosine
Type:
Small organic molecule
Emp. Form.:
C20H41NO2
Mol. Mass.:
327.545
SMILES:
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)N(C)C |r|
Structure:
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