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Target
Glycerol kinase
Ligand
BDBM50366482
Substrate
n/a
Meas. Tech.
ChEBML_72907
Ki
80000±n/a nM
Citation
 Bystrom, CE; Pettigrew, DW; Remington, S; Branchaud, BP ATP analogs with non-transferable groups in the position as inhibitors of glycerol kinase Bioorg Med Chem Lett 7:2613-2616 (1997)    Article 
Target
Name:
Glycerol kinase
Synonyms:
GK | GLPK_HUMAN
Type:
PROTEIN
Mol. Mass.:
61243.96
Organism:
Homo sapiens (Human)
Description:
ChEMBL_72907
Residue:
559
Sequence:
MAASKKAVLGPLVGAVDQGTSSTRFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDISNIKAIGVSNQRETTVVWDKITGEPLYNAVVWLDLRTQSTVESLSKRIPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGGVNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISHSVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAYKLGRDKPVYYALEGSVAIAGAVIRWLRDNLGIIKTSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGIICGLTQFTNKCHIAFAALEAVCFQTREILDAMNRDCGIPLSHLQVDGGMTSNKILMQLQADILYIPVVKPSMPETTALGAAMAAGAAEGVGVWSLEPEDLSAVTMERFEPQINAEESEIRYSTWKKAVMKSMGWVTTQSPESGDPSIFCSLPLGFFIVSSMVMLIGARYISGIP
  
Inhibitor
Name:
BDBM50366482
Synonyms:
CHEMBL1160358 | CHEMBL608908
Type:
Small organic molecule
Emp. Form.:
C11H16F2N5O12P3
Mol. Mass.:
541.1891
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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