Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50290900
Substrate
n/a
Meas. Tech.
ChEBML_29485
Ki
2.7±n/a nM
Citation
 Ha, SB; Melman, N; Jacobson, KA; Nair, V New base-altered adenosine analogues: Synthesis and affinity at adenosine A1 and A2A receptors Bioorg Med Chem Lett 7:3085-3090 (1997)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50290900
Synonyms:
(2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-((S)-2-hydroxy-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL321536
Type:
Small organic molecule
Emp. Form.:
C19H23N5O5
Mol. Mass.:
401.4164
SMILES:
CC(Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)[C@@H](O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: