Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50281135
Substrate
n/a
Meas. Tech.
ChEBML_29485
Ki
7.3±n/a nM
Citation
 Ha, SB; Melman, N; Jacobson, KA; Nair, V New base-altered adenosine analogues: Synthesis and affinity at adenosine A1 and A2A receptors Bioorg Med Chem Lett 7:3085-3090 (1997)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50281135
Synonyms:
(2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-(piperidin-1-ylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL313806
Type:
Small organic molecule
Emp. Form.:
C15H22N6O4
Mol. Mass.:
350.373
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NN3CCCCC3)ncnc12
Structure:
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