Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50281138
Substrate
n/a
Meas. Tech.
ChEBML_27607
Ki
8±n/a nM
Citation
 Ha, SB; Melman, N; Jacobson, KA; Nair, V New base-altered adenosine analogues: Synthesis and affinity at adenosine A1 and A2A receptors Bioorg Med Chem Lett 7:3085-3090 (1997)    Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50281138
Synonyms:
(2R,3R,4S,5R)-2-[2-Chloro-6-(morpholin-4-ylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL313306
Type:
Small organic molecule
Emp. Form.:
C14H19ClN6O5
Mol. Mass.:
386.791
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NN3CCOCC3)nc(Cl)nc12
Structure:
Search PDB for entries with ligand similarity: