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Target
Beta-mannosidase
Ligand
BDBM50366566
Substrate
n/a
Meas. Tech.
ChEBML_41367
Ki
17000±n/a nM
Citation
 Therisod, H; Letourneux, Y; Therisod, M A new strong inhibitor of beta-mannosidase. Bioorg Med Chem Lett 8:371-2 (1999) [PubMed]  Article 
Target
Name:
Beta-mannosidase
Synonyms:
Lysosomal beta A mannosidase | MANB1 | MANBA | MANBA_HUMAN | Mannanase | Mannase
Type:
PROTEIN
Mol. Mass.:
100878.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_41367
Residue:
879
Sequence:
MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQDSYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETDNMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNFVRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFDVVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDCWNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHELLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY
  
Inhibitor
Name:
BDBM50366566
Synonyms:
CHEMBL610071
Type:
Small organic molecule
Emp. Form.:
C6H10O6
Mol. Mass.:
178.14
SMILES:
OCC(O)[C@H]1OC(=O)[C@H](O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: