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Target
D(4) dopamine receptor
Ligand
BDBM50073802
Substrate
n/a
Meas. Tech.
ChEBML_60666
Ki
1800±n/a nM
Citation
 Löber, S; Hübner, H; Gmeiner, P Azaindole derivatives with high affinity for the dopamine D4 receptor: synthesis, ligand binding studies and comparison of molecular electrostatic potential maps. Bioorg Med Chem Lett 9:97-102 (1999) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50073802
Synonyms:
1-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyrazolo[5,1-a]isoquinoline | 4-(4-Chloro-phenyl)-1-pyrazolo[5,1-a]isoquinolin-1-ylmethyl-piperazin-1-ium | CHEMBL268558
Type:
Small organic molecule
Emp. Form.:
C22H21ClN4
Mol. Mass.:
376.882
SMILES:
Clc1ccc(cc1)N1CCN(Cc2cnn3ccc4ccccc4c23)CC1
Structure:
Search PDB for entries with ligand similarity: