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Target
Pancreatic alpha-amylase
Ligand
BDBM50090254
Substrate
n/a
Meas. Tech.
ChEMBL_34103 (CHEMBL649732)
Ki
<40000±n/a nM
Citation
 Gerrard, JA; Prince, MJ; Abell, AD Kinetic characterisation of ene-diol-based inhibitors of alpha-amylase. Bioorg Med Chem Lett 10:1575-6 (2000) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMYP_RAT | Amy2 | PA
Type:
PROTEIN
Mol. Mass.:
57186.64
Organism:
Rattus norvegicus
Description:
ChEMBL_34101
Residue:
508
Sequence:
MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL
  
Inhibitor
Name:
BDBM50090254
Synonyms:
(R)-5-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5H-furan-2-one | CHEMBL39670
Type:
Small organic molecule
Emp. Form.:
C9H12O6
Mol. Mass.:
216.188
SMILES:
CC1(C)OC[C@H](O1)c1oc(O)c(O)c1O
Structure:
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