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Target
Pancreatic alpha-amylase
Ligand
BDBM50351096
Substrate
n/a
Meas. Tech.
ChEMBL_34103 (CHEMBL649732)
Ki
43400±n/a nM
Citation
 Gerrard, JA; Prince, MJ; Abell, AD Kinetic characterisation of ene-diol-based inhibitors of alpha-amylase. Bioorg Med Chem Lett 10:1575-6 (2000) [PubMed]  Article 
Target
Name:
Pancreatic alpha-amylase
Synonyms:
1,4-alpha-D-glucan glucanohydrolase | AMYP_RAT | Amy2 | PA
Type:
PROTEIN
Mol. Mass.:
57186.64
Organism:
Rattus norvegicus
Description:
ChEMBL_34101
Residue:
508
Sequence:
MKFVLLLSLIGFCWAQYDPHTADGRTAIVHLFEWRWADIAKECERYLAPKGFGGVQVSPPNENIIINNPSRPWWERYQPISYKICSRSGNENEFKDMVTRCNNVGVRIYVDAVINHMCGSGNSAGTHSTCGSYFNPNNREFSAVPYSAWYFNDNKCNGEINNYNDANQVRNCRLSGLLDLALDKDYVRTKVADYMNNLIDIGVAGFRLDAAKHMWPGDIKAVLDKLHNLNTKWFSQGSRPFIFQEVIDLGGEAIKGSEYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPTDRALVFVDNHDNQRGHGAGGASILTFWDARMYKMAVGFMLAHPYGFTRVMSSYRRTRNFQNGKDVNDWIGPPNNNGVTKEVTINPDTTCGNDWVCEHRWRQIRNMVAFRNVVNGQPFANWWDNGSNQVAFSRGNRGFIVFNNDDWALSSTLQTGLPAGTYCDVISGDKVNGNCTGLKVNVGSDGKAHFSISNSAEDPFIAIHADSKL
  
Inhibitor
Name:
BDBM50351096
Synonyms:
ASCORBIC ACID
Type:
Small organic molecule
Emp. Form.:
C6H8O6
Mol. Mass.:
176.1241
SMILES:
OC[C@H](O)[C@H]1OC(=O)C(=O)C1O |r|
Structure:
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