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Target
Mu-type opioid receptor
Ligand
BDBM50101289
Substrate
n/a
Meas. Tech.
ChEBML_149137
Ki
3910±n/a nM
Citation
 Nortey, SO; Baxter, EW; Codd, EE; Zhang, SP; Reitz, AB Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor. Bioorg Med Chem Lett 11:1741-3 (2001) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50101289
Synonyms:
4-{(4-Ethyl-piperazin-1-yl)-[(Z)-2-methoxy-phenylimino]-methyl}-N,N-dipropyl-benzamide | CHEMBL48883
Type:
Small organic molecule
Emp. Form.:
C27H38N4O2
Mol. Mass.:
450.6162
SMILES:
CCCN(CCC)C(=O)c1ccc(cc1)C(=N\c1ccccc1OC)\N1CCN(CC)CC1
Structure:
Search PDB for entries with ligand similarity: