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Target
Beta-glucosidase
Ligand
BDBM50104295
Substrate
n/a
Meas. Tech.
ChEBML_37428
IC50
550000±n/a nM
Citation
 Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett 11:2489-93 (2001) [PubMed]  Article 
Target
Name:
Beta-glucosidase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
60428.49
Organism:
Prunus avium
Description:
ChEMBL_37428
Residue:
531
Sequence:
LLLLGFALANTNAARTDPPVVCATLNRTNFDTLFPGFTFGTATASYQLEGAANIDGRGPSIWDAFTHNHPEKITDGSNGDVAIDQYHRYKEDVAIMKDMGLDAYRFSISWSRLLPNGTLSGGINKKGIEYYNNLTNELIRNGIEPLVTLFHWDVPQALEEEYGGVLSPRIVYDFKAYAELCYKEFGDRVKHWTTLNEPYTISNHGYTIGIHAPGRCSSWYDPTCLGGDSGTEPYLVTHNLLLAHAAAVKLYREKYQASQEGVIGITVVSHWFEPASESQKDINASVRALDFMYGWFMDPLTRGDYPQSMRSLVKERLPNFTEEQSKSLIGSYDYIGVNYYSARYASAYPEDYSIPTPPSYLTDAYVNVTTELNGVPIGPQAASDWLYVYPKGLYDLVLYTKNKYNDPIMYITENGMDEFNNPKISLEQALNDSNRIDYCYRHLCYLQEAIIEGANVQGYFAWSLLDNFEWSEGYTVRFGINYVDYDNGLKRHSKLSTHWFKNFLKRSSISKEKIRRCGNNNARARKFVYRI
  
Inhibitor
Name:
BDBM50104295
Synonyms:
2-[(2-Hydroxy-1-methyl-2,2-diphenyl-ethylamino)-methyl]-pyrrolidine-3,4-diol | CHEMBL421340
Type:
Small organic molecule
Emp. Form.:
C20H26N2O3
Mol. Mass.:
342.432
SMILES:
CC(NCC1NCC(O)C1O)C(O)(c1ccccc1)c1ccccc1
Structure:
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