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Target
D(4) dopamine receptor
Ligand
BDBM50104341
Substrate
n/a
Meas. Tech.
ChEBML_58947
EC50
31±n/a nM
Citation
 Einsiedel, J; Hübner, H; Gmeiner, P Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179). Bioorg Med Chem Lett 11:2533-6 (2001) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50104341
Synonyms:
1-Phenyl-4-((R)-2-phenyl-4,5-dihydro-1H-imidazol-4-ylmethyl)-piperazine; hydrochloride | CHEMBL540039
Type:
Small organic molecule
Emp. Form.:
C20H24N4
Mol. Mass.:
320.4314
SMILES:
C([C@H]1CNC(=N1)c1ccccc1)N1CCN(CC1)c1ccccc1 |c:4|
Structure:
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