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Target
D(3) dopamine receptor
Ligand
BDBM50104344
Substrate
n/a
Meas. Tech.
ChEMBL_62299 (CHEMBL675221)
Ki
2500±n/a nM
Citation
 Einsiedel, J; Hübner, H; Gmeiner, P Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179). Bioorg Med Chem Lett 11:2533-6 (2001) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50104344
Synonyms:
1-[(4S,5R)-2-(5-Bromo-2-methoxy-phenyl)-5-methyl-4,5-dihydro-oxazol-4-ylmethyl]-4-phenyl-piperazine | CHEMBL315564
Type:
Small organic molecule
Emp. Form.:
C22H26BrN3O2
Mol. Mass.:
444.365
SMILES:
COc1ccc(Br)cc1C1=N[C@@H](CN2CCN(CC2)c2ccccc2)[C@@H](C)O1 |t:10|
Structure:
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