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Target
Tissue alpha-L-fucosidase
Ligand
BDBM50104399
Substrate
n/a
Meas. Tech.
ChEBML_34082
Ki
680±n/a nM
Citation
 Robina, I; Moreno-Vargas, AJ; Fernández-Bolaños, JG; Fuentes, J; Demange, R; Vogel, P New leads for selective inhibitors of alpha-L-fucosidases. Synthesis and glycosidase inhibitory activities of [(2R,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]furan derivatives. Bioorg Med Chem Lett 11:2555-9 (2001) [PubMed]  Article 
Target
Name:
Tissue alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase I | Alpha-L-fucoside fucohydrolase | FUCA1 | FUCO_HUMAN | Tissue alpha-L-fucosidase
Type:
PROTEIN
Mol. Mass.:
53690.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34088
Residue:
466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGVFIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEWADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYGLYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYWNSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSIDKFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGKWLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTKITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
  
Inhibitor
Name:
BDBM50104399
Synonyms:
(R)-4-Benzylamino-5-methyl-cyclopentane-1,2,3-triol | CHEMBL85171
Type:
Small organic molecule
Emp. Form.:
C13H19NO3
Mol. Mass.:
237.2949
SMILES:
CC1C(O)[C@@H](O)C(O)C1NCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: