Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50366766
Substrate
n/a
Meas. Tech.
ChEBML_31691
Ki
28±n/a nM
Citation
 Macchia, M; Salvetti, F; Bertini, S; Di Bussolo, V; Gattuso, L; Gesi, M; Hamdan, M; Klotz, KN; Laragione, T; Lucacchini, A; Minutolo, F; Nencetti, S; Papi, C; Tuscano, D; Martini, C 7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors. Bioorg Med Chem Lett 11:3023-6 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50366766
Synonyms:
CHEMBL611562
Type:
Small organic molecule
Emp. Form.:
C28H38N10O7
Mol. Mass.:
626.6641
SMILES:
CCNC(=O)C1OC(C(O)C1O)n1cnc2c(NCCCCCCCCCCNc3ccc([N+]([O-])=O)c4[n-][o+]nc34)ncnc12
Structure:
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