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Target
Beta-lactamase
Ligand
BDBM50112048
Substrate
n/a
Meas. Tech.
ChEBML_47853
IC50
3000±n/a nM
Citation
 Copar, A; Prevec, T; Anzic, B; Mesar, T; Selic, L; Vilar, M; Solmajer, T Design, synthesis and bioactivity evaluation of tribactam beta lactamase inhibitors. Bioorg Med Chem Lett 12:971-5 (2002) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase class C
Type:
PROTEIN
Mol. Mass.:
41618.07
Organism:
Enterobacter cloacae
Description:
ChEMBL_47855
Residue:
384
Sequence:
MMKKSLCCALLLGISCSALATPVSEKQLAEVVANTVTPLMKAQSVPGMAVAVIYQGKPHYYTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDPVTRYWPQLTGKQWQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGALAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRAVRVSPGMLDAQAYGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEANTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLANTSYPNPARVEAAYHILEALQ
  
Inhibitor
Name:
BDBM50112048
Synonyms:
CHEMBL368418 | Sodium; (S)-1-eth-(E)-ylidene-2-oxo-1,2,5,6,7,8,8a,8b-octahydro-azeto[2,1-a]isoindole-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C13H14NO3
Mol. Mass.:
232.2557
SMILES:
C\C=C1/[C@@H]2C3CCCCC3=C(N2C1=O)C([O-])=O |c:10|
Structure:
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