Reaction Details Report a problem with these data
Target
Tyrosinase
Ligand
BDBM60928
Substrate
n/a
Meas. Tech.
ChEMBL_213287 (CHEMBL814342)
IC50
8400000±n/a nM
Citation
 Nihei, K; Kubo, I Identification of oxidation product of arbutin in mushroom tyrosinase assay system. Bioorg Med Chem Lett 13:2409-12 (2003) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Homo sapiens (Human)
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM60928
Synonyms:
BDBM50130192 | L-3,4-dihydroxyphenylalanine | L-DOPA | US11021454, Compound L-dopa | dihydroxyphenylalanine
Type:
n/a
Emp. Form.:
C9H11NO4
Mol. Mass.:
197.1879
SMILES:
N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O |r|
Structure:
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