Reaction Details Report a problem with these data
Target
Peptide deformylase
Ligand
BDBM50131330
Substrate
n/a
Meas. Tech.
ChEBML_154179
IC50
400±n/a nM
Citation
 Davies, SJ; Ayscough, AP; Beckett, RP; Clements, JM; Doel, S; Pratt, LM; Spavold, ZM; Thomas, SW; Whittaker, M Structure--activity relationships of the peptide deformylase inhibitor BB-3497: modification of the P2' and P3' side chains. Bioorg Med Chem Lett 13:2715-8 (2003) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50131330
Synonyms:
1-{(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoyl}-pyrrolidine-2-carboxylic acid (S)-dimethyl-amide
Type:
Small organic molecule
Emp. Form.:
C15H27N3O4
Mol. Mass.:
313.3926
SMILES:
CCCC[C@H](CN(O)C=O)C(=O)N1CCCC1C(=O)N(C)C
Structure:
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