Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50404326
Substrate
n/a
Meas. Tech.
ChEBML_148227
Ki
279±n/a nM
Citation
 Chen, Z; Goehring, RR; Valenzano, KJ; Kyle, DJ Design and synthesis of novel small molecule N/OFQ receptor antagonists. Bioorg Med Chem Lett 14:1347-51 (2004) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50404326
Synonyms:
CHEMBL2113273
Type:
Small organic molecule
Emp. Form.:
C24H41N3O
Mol. Mass.:
387.6018
SMILES:
CCN1[C@@H]2CCCC[C@H]2N(C2CCN(CC2)C2CCC3CCCCC3C2)C1=O
Structure:
Search PDB for entries with ligand similarity: