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Target
Mu-type opioid receptor
Ligand
BDBM50140744
Substrate
n/a
Meas. Tech.
ChEBML_148227
Ki
199±n/a nM
Citation
 Chen, Z; Goehring, RR; Valenzano, KJ; Kyle, DJ Design and synthesis of novel small molecule N/OFQ receptor antagonists. Bioorg Med Chem Lett 14:1347-51 (2004) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50140744
Synonyms:
(3aR,7aR)-1-Ethyl-3-(1-naphthalen-2-ylmethyl-piperidin-4-yl)-octahydro-benzoimidazol-2-one | CHEMBL283301
Type:
Small organic molecule
Emp. Form.:
C25H33N3O
Mol. Mass.:
391.549
SMILES:
CCN1[C@@H]2CCCC[C@H]2N(C2CCN(Cc3ccc4ccccc4c3)CC2)C1=O
Structure:
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