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Target
D(1A) dopamine receptor
Ligand
BDBM50025210
Substrate
n/a
Meas. Tech.
ChEBML_58658
Ki
1790±n/a nM
Citation
 Ladd, DL; Weinstock, J; Wise, M; Gessner, GW; Sawyer, JL; Flaim, KE Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes. J Med Chem 29:1904-12 (1986) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49429.75
Organism:
RAT
Description:
P18901
Residue:
446
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
  
Inhibitor
Name:
BDBM50025210
Synonyms:
6-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | CHEMBL54168
Type:
Small organic molecule
Emp. Form.:
C16H17NO2
Mol. Mass.:
255.3117
SMILES:
Oc1cc2CCNCCc2c(c1O)-c1ccccc1
Structure:
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