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Target
D(2) dopamine receptor
Ligand
BDBM50019430
Substrate
n/a
Meas. Tech.
ChEBML_58559
IC50
710±n/a nM
Citation
 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL Buspirone analogues. 2. Structure-activity relationships of aromatic imide derivatives. J Med Chem 29:1476-82 (1986) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50019430
Synonyms:
2-(4-{4-[3-(4-Fluoro-phenyl)-3-methyl-2,5-dioxo-pyrrolidin-1-yl]-butyl}-piperazin-1-yl)-nicotinonitrile | CHEMBL35538
Type:
Small organic molecule
Emp. Form.:
C25H28FN5O2
Mol. Mass.:
449.5205
SMILES:
CC1(CC(=O)N(CCCCN2CCN(CC2)c2ncccc2C#N)C1=O)c1ccc(F)cc1
Structure:
Search PDB for entries with ligand similarity: