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Target
D(2) dopamine receptor
Ligand
BDBM50024706
Substrate
n/a
Meas. Tech.
ChEMBL_59178 (CHEMBL672642)
IC50
170±n/a nM
Citation
 Hall, AW; Taylor, RJ; Simmonds, SH; Strange, PG Synthesis of some [N-(2-haloalkyl)amino]tetralin derivatives as potential irreversible labels for bovine anterior pituitary D2 dopamine receptors. J Med Chem 30:1879-87 (1987) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50024706
Synonyms:
6-(2-Bromo-ethylamino)-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide | CHEMBL542624
Type:
Small organic molecule
Emp. Form.:
C12H16BrNO2
Mol. Mass.:
286.165
SMILES:
Oc1cc2CCC(Cc2cc1O)NCCBr
Structure:
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