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Target
Dipeptidase 1
Ligand
BDBM50024024
Substrate
n/a
Meas. Tech.
ChEBML_216035
Ki
30±n/a nM
Citation
 Graham, DW; Ashton, WT; Barash, L; Brown, JE; Brown, RD; Canning, LF; Chen, A; Springer, JP; Rogers, EF Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids. J Med Chem 30:1074-90 (1987) [PubMed]  Article 
Target
Name:
Dipeptidase 1
Synonyms:
DPEP1 | DPEP1_PIG | Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase | RDP | Renal dipeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44697.32
Organism:
GUINEA PIG
Description:
Leukotriene D4 Alpha 0 GUINEA PIG::P22412
Residue:
409
Sequence:
MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSSLAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVGFGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHAQVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
  
Inhibitor
Name:
BDBM50024024
Synonyms:
2-[(2,2-Dibromo-cyclopropanecarbonyl)-amino]-but-2-enoic acid | CHEMBL268228
Type:
Small organic molecule
Emp. Form.:
C8H9Br2NO3
Mol. Mass.:
326.97
SMILES:
C\C=C(/NC(=O)C1CC1(Br)Br)C(O)=O
Structure:
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