Reaction Details Report a problem with these data
Target
Aminopeptidase B
Ligand
BDBM50022743
Substrate
n/a
Meas. Tech.
ChEBML_35352
Ki
0.910000±n/a nM
Citation
 Ocain, TD; Rich, DH Synthesis of sulfur-containing analogues of bestatin. Inhibition of aminopeptidases by alpha-thiolbestatin analogues. J Med Chem 31:2193-9 (1988) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep
Type:
PROTEIN
Mol. Mass.:
72609.93
Organism:
Rattus norvegicus
Description:
ChEMBL_1344423
Residue:
650
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
  
Inhibitor
Name:
BDBM50022743
Synonyms:
2,6-Diamino-hexane-1-thiol | CHEMBL68509
Type:
Small organic molecule
Emp. Form.:
C6H16N2S
Mol. Mass.:
148.27
SMILES:
NCCCC[C@@H](N)CS
Structure:
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