Reaction Details Report a problem with these data
Target
Aminopeptidase B
Ligand
BDBM50022754
Substrate
n/a
Meas. Tech.
ChEBML_35352
Ki
35700±n/a nM
Citation
 Ocain, TD; Rich, DH Synthesis of sulfur-containing analogues of bestatin. Inhibition of aminopeptidases by alpha-thiolbestatin analogues. J Med Chem 31:2193-9 (1988) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_RAT | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | Cytosol aminopeptidase IV | Rnpep
Type:
PROTEIN
Mol. Mass.:
72609.93
Organism:
Rattus norvegicus
Description:
ChEMBL_1344423
Residue:
650
Sequence:
MESSGPSSCHSAARRPLHSAQAVDVASASSFRAFEILHLHLDLRAEFGPPGPGPGSRGLNGKATLELRCLLPEGASELRLDSHSCLEVMAATLLRGQPGDQQQLTEPVPFHTQPFSHYGQALCVVFPKPCCAAERFRLELTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTWERRGPNKFFFQMSQPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFNRWLNTPGWPPYLPDLSPGDSLMKPAEELAELWAASEPDMQAIEAVAISTWKTYQLVYFLDKILQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDHQEEFWKVKDFLQSQGKQKYTLPLYHAMMGGSEMARTLAKETFSATASQLHSNVVNYVQQILAPKGS
  
Inhibitor
Name:
BDBM50022754
Synonyms:
3-Amino-2-mercapto-N-(3-methyl-butyl)-4-phenyl-butyramide | CHEMBL69238
Type:
Small organic molecule
Emp. Form.:
C15H24N2OS
Mol. Mass.:
280.429
SMILES:
CC(C)CCNC(=O)[C@H](S)[C@@H](N)Cc1ccccc1
Structure:
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